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Invitrogen
Phospho-IP3 Receptor 1 (Tyr353) Polyclonal Antibody
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Phospho-IP3 Receptor 1 (Tyr353) Antibody (PA5-106062) in WB
Western blot analysis of Phospho-IP3 Receptor 1 (Tyr353) in HeLa cell lysate (absence (-) or presence (+) of non-phospho and phospho peptide). Samples were incubated with Phospho-IP3 Receptor 1 (Tyr353) polyclonal antibody (Product # PA5-106062).
产品信息
PA5-106062
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ITPR1(Accession Q14643), corresponding to amino acid residues around phosphorylated Tyr353.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of IP3 Receptor only when phosphorylated at Tyr353.
靶标信息
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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