Invitrogen

Phospho-JunB (Thr102, Thr104) Polyclonal Antibody

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说明书
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Phospho-JunB (Thr102, Thr104) Polyclonal Antibody

产品信息

PA5-104603

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:50-1:200
-

免疫细胞化学 (ICC/IF)

1:100-1:500
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human JUNB(Accession P17275), corresponding to amino acid residues around phosphorylated Thr102.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2816078

产品详细信息

Antibody detects endogenous levels of JunB only when phosphorylated at Thr102/Thr104.

靶标信息

JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB

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基因别名: AP-1; Jun-b; JUNB

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UniProt ID: (Human) P17275, (Rat) P24898, (Mouse) P09450

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Entrez Gene ID: (Human) 3726, (Rat) 24517, (Mouse) 16477

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功能
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription coactivator activity transcription corepressor activity protein binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding protein heterodimerization activity basic leucine zipper transcription factor
参与通路
negative regulation of transcription from RNA polymerase II promoter vasculogenesis osteoblast differentiation trophectodermal cell differentiation regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter response to radiation response to light stimulus response to mechanical stimulus regulation of cell death osteoclast differentiation response to lipopolysaccharide response to progesterone cellular response to hormone stimulus osteoblast proliferation response to cytokine regulation of cell proliferation response to drug response to peptide hormone positive regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter decidualization response to corticosterone response to cAMP regulation of cell cycle embryonic process involved in female pregnancy labyrinthine layer blood vessel development cellular response to calcium ion in utero embryonic development regulation of transcription, DNA-templated female pregnancy cellular process response to organic cyclic compound transcription, DNA-templated
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