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Invitrogen
Phospho-PKA alpha/beta (Thr197) Polyclonal Antibody
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产品信息
PA1-28490
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide derived from a region of human PKA that contains threonine 197.
偶联物
形式
Liquid
浓度
0.35 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-28490 detects PKA alpha + beta from mouse, human samples.
PA1-28490 has been successfully used in Western blot applications.
The PA1-28490 immunogen is: Synthetic phosphopeptide derived from a region of human PKA that contains threonine 197.
靶标信息
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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