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Invitrogen
Phospho-RAD17 (Ser647) Polyclonal Antibody
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Phospho-RAD17 (Ser647) Antibody (PA1-41545) in WB
Western blot analysis of Rad17-phos in A) a partial recombinant protein containing phospho Ser647 and B) the same sequence without the phospho serine, and was blocked using the non-phospho control of the immunizing peptide, using a Phospho-RAD17 pSer647 polyclonal antibody (Product # PA1-41545) 0.1 µg/mL
产品信息
PA1-41545
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide corresponding to residues 644-652 L(644) P L S(p) Q N S G S(652) of mouse Rad17.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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