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Invitrogen
Phospho-RSK1 (Ser221) Polyclonal Antibody
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产品信息
PA1-24769
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide corresponding to a portion of human RSK1 containing serine 221.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-24769 detects RSK1 p90 (phospho S221) from human samples. PA1-24769 is expected to cross react with mouse (100% conserved) and rat (100% conserved) due to sequence homology. Cross reactivity with RSK2 is expected (100% conserved). Cross reactivity with RSK3 (80% homology) and RSK4 (90% homology) is possible but has not been tested. Not yet tested in other species.
PA1-24769 has been successfully used in Western blot procedures. A431 and NIH3T3 cells treated with PMA can be used as a positive control for this antibody.
The PA1-24769 immunogen is a synthetic phosphopeptide corresponding to a portion of human RSK1 containing serine 221.
Store at 4C short term. For extended storage, aliquot and store at -20C or below, avoiding freeze-thaw cycles.
靶标信息
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase that is involved in the MAPK cascade. It is thought to control cellular proliferation and differentiation through the phosphorylation of transcription factors. RPS6KA1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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