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Invitrogen
Phospho-Rac GTPase Activating Protein 1 (Ser387) Polyclonal Antibody
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Phospho-Rac GTPase Activating Protein 1 (Ser387) Antibody (PA5-35528) in WB
Western blot analysis of Phospho-Rac GTPase Activating Protein 1 pSer387 in COS7 whole cell lysates with a blocking peptide (lane 1) and no blocking peptide (lane 2) using a Phospho-Rac GTPase Activating Protein 1 pSer387 polyclonal antibody (Product # PA5-35528).
产品信息
PA5-35528
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from human GTPase Activating Protein around the phosphorylation site of Serine 387
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
靶标信息
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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