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Invitrogen
Phospho-Rb (Thr356) Monoclonal Antibody (7F10)
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产品信息
MA1-90305
产品规格
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
7F10
抗原
considered to be commercially sensitive
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
MA1-90305 detects RB1 from mouse, human samples.
MA1-90305 has been successfully used in immunohistochemistry (frozen tissue) and Western blot applications, where a band of 111.4 kDa is predicted to be determined.
The MA1-90305 immunogen is considered to be commercially sensitive.
Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles.
靶标信息
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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