Search
Invitrogen
Phospho-TAL1 (Ser122) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
Phospho-TAL1 (Ser122) Antibody (PA5-37752) in WB
Western Blot analysis of Phospho-TAL1 (Ser122) was performed using extracts from JK cells (Lane 2). The lane on the left is treated with antigen-specific peptide. The membrane was probed with Phospho-TAL1 (Ser122) Polyclonal Antibody (Product # PA5-37752).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-37752
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control for Western blot is JK cells.
靶标信息
TAL-1 is a basic helix-loop-helix transcription. It regulates differentiation and survival during hemopoiesis. TAL-1 is also implicated in the genesis of hemopoietic malignancies and it may play an important role in hemopoietic differentiation. It serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. TAL-1 is know to bind to the LIM domain containing protein Rhombotin-2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: HGNC:11556; Stem cell protein; T-cell acute lymphocytic leukemia 1; T-cell acute lymphocytic leukemia protein 1 homolog; TAL-1
基因别名: bHLHa17; Scl; SCL/tal-1; Tal-1; Tal1
UniProt ID: (Mouse) P22091
Entrez Gene ID: (Mouse) 21349
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
enzyme binding
histone deacetylase binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
E-box binding
basic helix-loop-helix transcription factor
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
locomotory behavior
spinal cord association neuron differentiation
hemopoiesis
myeloid cell differentiation
cell differentiation
neuron differentiation
erythrocyte differentiation
megakaryocyte differentiation
platelet formation
positive regulation of protein complex assembly
embryonic hemopoiesis
megakaryocyte development
regulation of cell proliferation
erythrocyte maturation
cell fate commitment
regulation of myeloid cell differentiation
positive regulation of erythrocyte differentiation
positive regulation of chromatin assembly or disassembly
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
generation of neurons
positive regulation of cell division
astrocyte fate commitment
definitive hemopoiesis
hemangioblast cell differentiation
hematopoietic stem cell differentiation
regulation of mast cell differentiation
regulation of stem cell population maintenance
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
