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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: liver regeneration-related protein LRRG079; putative MAPK-activating protein PM14; putative NF-kappa-B-activating protein 20; TIFAA; TRAF-interacting protein with a forkhead-associated domain; TRAF2 binding protein; TRAF2-binding protein; TRAF6 binding protein; unnamed protein product
基因别名: Ab2-389; T2BP; T6BP; TIFAA
UniProt ID: (Human) Q96CG3, (Mouse) Q793I8, (Rat) Q5XIB9
Entrez Gene ID: (Human) 92610, (Mouse) 211550, (Rat) 310877