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Invitrogen
Phospho-VAV1 (Tyr160) Polyclonal Antibody
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产品信息
PA1-26651
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide corresponding to a portion of human VAV 1 containing tyrosine 160. The sequence is conserved in mouse and rat.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-26651 detects VAV1 (phospho Y160) from human samples. PA1-26651 is expected to cross react with mouse, rat, and a wide range of other species due to sequence homology.
PA1-26651 has been successfully used in Western blot procedures.
The PA1-26651 immunogen is a synthetic phosphopeptide corresponding to a portion of human VAV 1 containing tyrosine 160. The sequence is conserved in mouse and rat.
靶标信息
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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