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Invitrogen
Phospho-cGKII (Ser126) Polyclonal Antibody
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Phospho-cGKII (Ser126) Antibody (PA5-118661) in IHC (P)
Immunohistochemical analysis of Phospho-cGKII (Ser126) in Human pancreas tissue using a Phospho-cGKII (Ser126) polyclonal antibody (Product # PA5-118661). The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the se... View More
产品信息
PA5-118661
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CGK2 around the phosphorylation site of Ser126.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
靶标信息
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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