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Alomone Labs, LTD
Plexin-A4 (extracellular) Polyclonal Antibody
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Plexin-A4 (extracellular) Antibody (APR-084-200UL) in IHC (F)
Expression of Plexin-A4 in rat hippocampus. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-Plexin-A4 (extracellular) Antibody (#APR-084) (1:300), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal mossy fiber terminal zone (MFT), showed Plexin-A4 immunoreactivity (green) in a zone adjacent to the pyramidal layer (horizontal arrows). B. Pre-incuba... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
APR-084-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide CESFNVTGELYWTKVK, corresponding to amino acid residues 1386-1401 of mouse SCN5A. Extracellular, 11th loop.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: CESFNVTGELYWTKVK
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
PLXNA4 is a protein coding gene. Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis secretory sperm binding protein; OTTHUMP00000207245; plexin A4, A; unnamed protein product
基因别名: 9330117B14; FAYV2820; mKIAA1550; PLEXA4; Plxa4; PLXNA4A; PLXNA4B; PRO34003
UniProt ID: (Human) Q9HCM2, (Mouse) Q80UG2
Entrez Gene ID: (Human) 91584, (Rat) 312213, (Mouse) 243743
nervous system development
axon guidance
synapse assembly
motor neuron axon guidance
telencephalon development
cranial nerve morphogenesis
facial nerve morphogenesis
facial nerve structural organization
glossopharyngeal nerve morphogenesis
trigeminal nerve morphogenesis
trigeminal nerve structural organization
vagus nerve morphogenesis
postganglionic parasympathetic fiber development
branchiomotor neuron axon guidance
chemorepulsion of branchiomotor axon
central nervous system neuron development
anterior commissure morphogenesis
regulation of cell migration
embryonic heart tube development
tube development
sympathetic nervous system development
neuron projection morphogenesis
regulation of axon extension involved in axon guidance
negative chemotaxis
regulation of chemotaxis
regulation of negative chemotaxis
epithelium development
semaphorin-plexin signaling pathway
sympathetic neuron axon guidance
maintenance of synapse structure
regulation of plasma membrane bounded cell projection organization
cell surface receptor signaling pathway
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