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Polycystin 2 Polyclonal Antibody
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产品信息
BS-2158R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human Polycystin 2, amino acids 651-750.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Polycystin-2 (PC2), encoded by the PKD2 gene, is a multi-pass membrane protein that functions as a nonselective calcium-permeable cation channel, primarily localized to the primary cilium and endoplasmic reticulum. It plays a key role in calcium signaling and mechanosensation, often forming a complex with polycystin-1 to regulate cellular responses to fluid flow. Mutations in PKD2 disrupt these processes and lead to autosomal dominant polycystic kidney disease (ADPKD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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