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Invitrogen
Protease-Activated Receptor-4 Polyclonal Antibody
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Protease-Activated Receptor-4 Antibody (PA5-75411) in WB
Western blot analysis of Protease-Activated Receptor-4 in Lane 1: A549 whole cell lysate, Lane 2: Raw264.7 whole cell lysate, Lane 3: PC12 whole cell lysate. Samples were incubated with Protease-Activated Receptor-4 polyclonal antibody (Product # PA5-75411) at a dilution of 1:500.
产品信息
PA5-75411
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 34-87 of Human F2RL3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
15mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; PAR-4; protease-activated receptor 4; protease-activated receptor-4; Proteinase-activated receptor 4; Thrombin receptor-like 3
基因别名: F2RL3; PAR4
UniProt ID: (Human) Q96RI0, (Rat) Q920E0, (Mouse) O88634
Entrez Gene ID: (Human) 9002, (Rat) 116498, (Mouse) 14065
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
blood coagulation
response to wounding
platelet activation
positive regulation of release of sequestered calcium ion into cytosol
platelet dense granule organization
thrombin receptor signaling pathway
G-protein coupled receptor signaling pathway
hemostasis
