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Invitrogen
Protein C (Active) Monoclonal Antibody (PC107)
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产品信息
MA5-49088
产品规格
种属反应
Human
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
PC107
抗原
Monoclonal antibody PC107 is specific for activated Protein C (APC
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein G
保存液
PBS with 0.1% BSA
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The monoclonal antibody PC107 is specific for activated human protein C (APC) and it lacks reactivity for Protein C. The monoclonal antibody recognizes the light chain of the APC molecule.
靶标信息
Protein C is a protein that plays a crucial role in the regulation of blood clotting. It is a vitamin K-dependent serine protease that is activated by thrombin, a protein that promotes blood clotting. Once activated, protein C proteolytically cleaves and inactivates factors V and VIII, which are essential for the formation of blood clots. This process helps to prevent excessive blood clotting and maintain the normal flow of blood through the body. In addition to its anticoagulant function, protein C has also been shown to have anti-inflammatory and cytoprotective properties, suggesting that it may have a broader role in maintaining vascular health.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Active Protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; prepro-protein C; protein C (inactivator of coagulation factors Va and VIIIa); type I protein C; Vitamin K-dependent protein C
基因别名: APC; PC; PROC; PROC1; THPH3; THPH4
UniProt ID: (Human) P04070
Entrez Gene ID: (Human) 5624
signal peptide processing
proteolysis
ER to Golgi vesicle-mediated transport
blood coagulation
peptidyl-glutamic acid carboxylation
negative regulation of blood coagulation
negative regulation of apoptotic process
negative regulation of inflammatory response
negative regulation of coagulation
leukocyte migration
positive regulation of establishment of endothelial barrier
