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Invitrogen
Protogenin Polyclonal Antibody
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产品信息
PA5-56940
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human Protogenin
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: HYIIDDLEPA SNYTFYIVAY MPMGASQMSD HVTQNTLEDV PLRPPEISLT SRSPTDILIS WLPIPAKYRR GQVVLYRLSF R
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 99%.
靶标信息
Protogenin, encoded by the PRTG gene, is a cell surface protein that belongs to the immunoglobulin superfamily and plays a critical role in neural development. Protogenin is involved in cell adhesion and signaling pathways that regulate processes such as neurogenesis, neuronal migration, and the establishment of neural circuits during embryonic development. Its expression is predominantly observed in the developing nervous system, where it facilitates interactions between cells and the extracellular matrix, contributing to the proper formation of brain structures. Protogenin's function in regulating cellular communication is essential for maintaining the balance between stem cell renewal and differentiation in neural tissues. Dysregulation or mutations in the PRTG gene can lead to developmental abnormalities and have been investigated for their potential connections to neurodevelopmental disorders. Research continues to explore protogenin's mechanisms and interaction networks to better understand its contributions to neural development and its potential as a therapeutic target in developmental disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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