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Agrisera
Psc/Polycomb group protein Psc Polyclonal Antibody
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Psc/Polycomb group protein Psc Antibody (AS17-4129) in ChIP
ChIP and q PCR analysis were done as described (Schwartz et al., 2006. doi: 10.1,038/ng 1817). Chromatin from Psc/Su(z)2-KO cells (Kahn et al., 2016. doi: 10.1093/nar/gkw 701 ) served as a negative control (Psc minus), chromatin from Ras 3 cells served as a positive control (WT). Quantitative PCR was performed with primers specific for BXD-PRE of the Ubx gene (Polycomb target gene in the repressed state) an... View More
产品信息
AS17-4129
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
GST-conjugated, full length Psc protein of Drosophila melanogaster.
偶联物
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Drosophila melanogaster
靶标信息
Psc, Polycomb group protein Psc, is a chromatin regulator best characterized in animals as a core Polycomb repressive complex component that maintains transcriptional silencing of developmental genes through histone modification and chromatin compaction. It contributes to stable epigenetic memory of cell identity by promoting H2A ubiquitination with PRC1 and cooperating with PRC2 mediated H3K27 methylation. Plant genomes encode distinct Polycomb proteins rather than a direct Psc ortholog, but analogous PRC1 like and PRC2 complexes perform similar gene silencing functions to control meristem maintenance, flowering time, seed development, and stress responses. In plant associated datasets, a Psc annotation typically indicates animal or microbial origin, or a comparative reference to Polycomb repression rather than a native plant gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARA8; ARABIDOPSIS THALIANA PHYTOCHELATIN SYNTHASE 1; ATPCS1; CAD1; CADMIUM SENSITIVE 1; CG3886-PA; CG3886-PB; CG3886-PC; MRH10.18; MRH10_18; PCS1; PHYTOCHELATIN SYNTHASE; PHYTOCHELATIN SYNTHASE 1; Polycomb group protein Psc; posterior sex comb; posterior-sex-combs; Protein posterior sex combs; Psc-PA; Psc-PB; Psc-PC
基因别名: 49Ea; CG3886; D-Bmi; Dmel\CG3886; Dmel_CG3886; dPSC; l(2)49Ea; l(2)Psc; l(2)vr14; PSC; Psc1; Su(z)2-C; vr14
UniProt ID: (Fruit fly) P35820
Entrez Gene ID: (Fruit fly) 36431
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