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Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (91%), Chicken (91%), Chimpanzee (100%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GlnRS; Glutamine--tRNA ligase; glutamine-tRNA synthetase; Glutaminyl-tRNA synthetase
基因别名: GLNRS; MSCCA; PRO2195; QARS; QARS1
UniProt ID: (Human) P47897
Entrez Gene ID: (Human) 5859