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Invitrogen
RAB11A Polyclonal Antibody
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产品信息
PA1-31607
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence TENKPKVQCCQNI, from C Terminus of the protein sequence according to NP_004654
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-31607 detects Rab11A from mouse samples.
PA1-31607 has been successfully used in Western blot applications.
The PA1-31607 immunogen is: Peptide with sequence TENKPKVQCCQNI, from C Terminus of the protein sequence according to NP_004654
靶标信息
Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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