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Invitrogen
RAB34 Polyclonal Antibody
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RAB34 Antibody (PA5-87817) in WB
Western blot analysis of RAB34 in extracts of various cell lines. Samples were incubated with RAB34 Polyclonal antibody (Product # PA5-87817) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-87817
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human RAB34 (NP_1141404)
偶联物
形式
Liquid
浓度
1.52 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA SKKKPTCCP; Positive Samples: Mouse lung, Mouse brain, Mouse kidney, Mouse testis; Cellular Location: Nucleus, nucleolus
靶标信息
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nine amino-acid residue-repeats; rab-39; RAB34, member of RAS oncogene family; Ras-related homolog; Ras-related protein Rab-34; Ras-related protein Rab-34, isoform NARR; Ras-related protein Rab-39; Ras-related protein RAB34; Ras-related protein Rah
基因别名: AI326479; NARR; RAB34; RAB39; RAH; Rah1
UniProt ID: (Human) Q9BZG1, (Mouse) Q64008, (Rat) Q5U1Y1
Entrez Gene ID: (Human) 83871, (Mouse) 19376, (Rat) 360571
small GTPase mediated signal transduction
antigen processing and presentation
lysosome localization
Golgi to plasma membrane protein transport
macropinocytosis
protein localization to plasma membrane
phagosome maturation
phagosome-lysosome fusion
transport
endocytosis
protein transport
Rab protein signal transduction
intracellular protein transport
metabolic process
