Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
RAD17 Polyclonal Antibody, MaxPab™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
H00005884-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RAD17 (NP_579919.1, 1 a.a. approximately 584 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNQHELAVHK KKIEEVETWL KAQVLERQPK QGGSILLITG PPGCGKTTTL KILSKEHGIQ VQEWINPVLP DFQKDDFKGM FNTESSFHMF PYQSQIAVFK EFLLRATKYN KLQMLGDDLR TDKKIILVED LPNQFYRDSH TLHEVLRKYV RIGRCPLIFI ISDSLSGDNN QRLLFPKEIQ EECSISNISF NPVAPTIMMK FLNRIVTIEA NKNGGKITVP DKTSLELLCQ GCSGDIRSAI NSLQFSSSKG ENNLRPRKKG MSLKSDAVLS KSKRRKKPDR VFENQEVQAI GGKDVSLFLF RALGKILYCK RASLTELDSP RLPSHLSEYE RDTLLVEPEE VVEMSHMPGD LFNLYLHQNY IDFFMEIDDI VRASEFLSFA DILSGDWNTR SLLREYSTSI ATRGVMHSNK ARGYAHCQGG GSSFRPLHKP QWFLINKKYR ENCLAAKALF PDFCLPALCL QTQLLPYLAL LTIPMRNQAQ ISFIQDIGRL PLKRHFGRLK MEALTDREHG MIDPDSGDEA QLNGGHSAEE SLGEPTQATV PETWSLPLSQ NSASELPASQ PQPFSAQGDM EENIIIEDYE SDGT
靶标信息
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: cell cycle checkpoint protein (RAD17); Cell cycle checkpoint protein RAD17; FLJ41520; hRad17; RAD1 homolog; RAD17 (Ser647); RAD17 homolog; Rad17 like protein; Rad17-like protein; RF-C activator 1 homolog; RF-C/activator 1 homolog
基因别名: CCYC; HRAD17; R24L; RAD17; RAD17SP; RAD24
UniProt ID: (Human) O75943
Entrez Gene ID: (Human) 5884
