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Invitrogen
RAE1 delta Monoclonal Antibody (186107)
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RAE1 delta Antibody (MA5-23889) in Flow
Flow cytometry of RAE1 delta in RAW 264.7 mouse monocyte/macrophage cell line. Samples were incubated in RAE1 delta monoclonal antibody (Product # MA5-23889) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-23889
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
186107
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Rae-1delta Leu29-Ser227
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes Rae-1 alpha, beta, gamma, gamma and epsilon.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Rae-1 delta is one of several known murine NKG2D ligands that include RAE-1 molecules, H60 and MULT-1. Expression of NKG2D ligands is low or absent on normal adult tissues. However, stressed or transformed cells express NKG2D ligands which in turn activates NK cells tumoricidal activity through NKG2D. Until now, the expression of NKG2D ligands has been mainly studied with NKG2D tetramers which recognizes all NKG2D ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RAE-1 delta; GPI-anchored membrane glycoprotein; RAE-1-delta; retinoic acid early transcript 1D
基因别名: RAE-1delta
UniProt ID: (Mouse) Q9JI58
Entrez Gene ID: (Mouse) 56554
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
signal transduction
natural killer cell mediated cytotoxicity
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