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Abnova
RASAL1 Polyclonal Antibody, MaxPab™
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产品信息
H00008437-B01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RASAL1 (AAH14420.1, 1 a.a. approximately 776 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAKSSSLNVR VVEGRALPAK DVSGSSDPYC LVKVDDEVVA RTATVWRSLG PFWGEEYTVH LPLDFHQLAF YVLDEDTVGH DDIIGKISLS REAITADPRG IDSWINLSRV DPDAEVQGEI CLSVQMLEDG QGRCLRCHVL QARDLAPRDI SGTSDPFARV FWGSQSLETS TIKKTRFPHW DEVLELREMP GAPSPLRVEL WDWDMVGKND FLGMVEFSPK TLQQKPPKGW FRLLPFPRAE EDSGGNLGAL RVKVRLIEDR VLPSQCYQPL MELLMESVQG PAEEDTASPL ALLEELTLGD CRQDLATKLV KLFLGRGLAG HFLDYLTRRE VARTMDPNTL FRSNSLASKS MEQFMKLVGM PYLHEVLKPV ISRVFEEKKY MELDPCKMDL GRTRRISFKG ALSEEQMRET SLGLLTGYLG PIVDAIVGSV GRCPPAMRLA FKQLHRRVEE RFPQAEHQDV KYLAISGFLF LRFFAPAILT PKLFDLRDQH ADPQTSRSLL LLAKAVQSIG NLGQQLGQGK ELWMAPLHPF LLQCVSRVRD FLDRLVDVDG DEAGVPARAL FPPSAIVREG YLLKRKEEPA GLATRFAFKK RYVWLSGETL SFSKSPEWQV VTQDGTGALH TTYLQCKNVN ELNQWLSALR KASAPNPNKL AACHPGAFRS ARWTCCLQAE RSAAGCSRTH SAVTLGDWSD PLDPDAEAQT VYRQLLLGRD QLRLKLLEDS NMDTTLEADT GACPEVLARQ RAATARLLEV LADLDRAHEE FQQQERGKAA LGPLGP
靶标信息
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GAP1 like protein; Ras GTPase-activating-like protein; RAS protein activator like 1; RasGAP-activating-like protein 1
基因别名: RASAL; RASAL1
UniProt ID: (Human) O95294
Entrez Gene ID: (Human) 8437, (Rat) 360814
