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Invitrogen
RASGRF1 Recombinant Rabbit Monoclonal Antibody (K01_1P33)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA567847
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_1P33
抗原
A synthetic peptide of human CDC25.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 0.05% BSA, 40% glycerol, 150mM NaCl
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASPP1; guanine nucleotide-releasing protein; KIAA0771; PPP1R13B
基因别名: GNRP; P140 RAS-GRF
UniProt ID: (Rat) P28818
Entrez Gene ID: (Rat) 192213
response to amphetamine
small GTPase mediated signal transduction
Ras protein signal transduction
cell proliferation
neuron projection development
cellular response to insulin stimulus
response to endoplasmic reticulum stress
positive regulation of Rac protein signal transduction
intracellular signal transduction
negative regulation of MAPK cascade
positive regulation of MAPK cascade
positive regulation of GTPase activity
regulation of Ras protein signal transduction
positive regulation of Ras protein signal transduction
positive regulation of fibroblast proliferation
regulation of synaptic plasticity
regulation of neuronal synaptic plasticity
cellular response to antibiotic
activation of GTPase activity
postsynaptic modulation of chemical synaptic transmission
regulation of N-methyl-D-aspartate selective glutamate receptor activity
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