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Proteintech
RB1CC1 Polyclonal Antibody
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产品信息
17250-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RB1CC1 Fusion Protein Ag10508 (1241-1594 aa encoded by BC017556)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RB1CC1. the calculated molecular weight of RB1CC1 is 180 kDa, but the modified RB1CC1 is about 200 kDa.
Immunogen sequence: AIQTALKEF KLEREVVEKE LLEKVKHLEN QIAKSPAIDS TRGDSSSLVA ELQEKLQEEK AKFLEQLEEQ EKRKNEEMQN VRTSLIAEQQ TNFNTVLTRE KMRKENIIND LSDKLKSTMQ QQERDKDLIE SLSEDRARLL EEKKKLEEEV SKLRSSSFVP SPYVATAPEL YGACAPELPG ESDRSAVETA DEGRVDSAME TSMMSVQENI HMLSEEKQRI MLLERTLQLK EEENKRLNQR LMSQSMSSVS SRHSEKIAIR DFQVGDLVLI ILDERHDNYV LFTVSPTLYF LHSESLPALD LKPGEGASGA SRRPWVLGKV MEKEYCQAKK AQNRFKVPLG TKFYRVKAVS WNKKV (1241-1594 aa encoded by BC017556 )
靶标信息
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 200 kDa FAK family kinase-interacting protein; coiled coil forming protein 1; Coiled-coil-forming protein 1; FAK family kinase-interacting protein of 200 kDa; FIP200; LaXp180; phosphatase 1, regulatory subunit 131; RB1-inducible coiled-coil 1; RB1-inducible coiled-coil protein 1
基因别名: 2900055E04Rik; 5930404L04Rik; ATG17; CC1; FIP200; KIAA0203; LaXp180; PPP1R131; RB1CC1; RBICC
UniProt ID: (Human) Q8TDY2, (Mouse) Q9ESK9
Entrez Gene ID: (Human) 9821, (Mouse) 12421, (Rat) 312927
autophagosome assembly
liver development
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
autophagy
cell cycle
JNK cascade
heart development
regulation of autophagy
macroautophagy
positive regulation of cell size
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of apoptotic process
biological_process
