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Invitrogen
RDM1 Polyclonal Antibody
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RDM1 Antibody (PA5-93244) in WB
Western blot analysis of RDM1 in extracts of various cell lines. Samples were incubated with RDM1 Polyclonal antibody (Product # PA5-93244) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-93244
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 125-284 of human RDM1 (NP_6636291)
偶联物
形式
Liquid
浓度
1.39 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NGCSKRIIKL QELSDLEERE NEDSMVPLPK QSLKFFCALE VVLPSCDCRS PGIGLVEEPM DKVEEGPLSF LMKRKTAQKL AIQKALSDAF QKLLIVVLES GKIAVEYRPS EDIVGVRCEE ELHGLIQVPC SPWKQYGQEE EGYLSDFSLE EEEFRLPELD; Positive Samples: Mouse kidney, Mouse heart, Mouse lung; Cellular Location: Cajal body, Cytoplasm, Nucleus, PML body, nucleolus
靶标信息
This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DeltaN-RDM1zeta; RAD52 homolog B; RAD52 motif-containing protein 1; RAD52B homolog
基因别名: 2410008M22Rik; AW212028; Rad52b; Rdm1
UniProt ID: (Mouse) Q9CQK3
Entrez Gene ID: (Mouse) 66599
