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Invitrogen
REST Polyclonal Antibody
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产品信息
PA5-34583
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 1050 to the C-terminus of Mouse REST / NRSF.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
For Western Blot, this antibody has non-specific bands at 53 kDa and 75 kDa.
Not suitable for use with Immunohistochemistry (Paraffin).
This antibody is predicted to react with rat based on sequence homology.
靶标信息
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
