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Invitrogen
RET Monoclonal Antibody (3F8)
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产品信息
MA5-11513
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3F8
抗原
Recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C
运输条件
Wet ice
产品详细信息
MA5-11513 targets Ret Oncoprotein in IHC (P) applications and shows reactivity with Human samples.
The MA5-11513 immunogen is recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein.
靶标信息
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. RET transduce signals for cell growth and differentiation. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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