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Proteintech
REV1 Polyclonal Antibody
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产品信息
17703-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
REV1 fusion protein Ag11975
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: SRPSVQSSHF PSGSYSVRDV FQVQKAKKST EEEHKEVFRA AVDLEISSAS RTCTFLPPFP AHLPTSPDTN KAESSGKWNG LHTPVSVQSR LNLSIEVPSP SQLDQSVLEA LPPDLREQVE QVCAVQQAES HGDKKKEPVN GCNTGILPQP VGTVLLQIPE PQESNSDAGI NLIALPAFSQ VDPEVFAALP AELQRELKAA YDQRQRQGEN STHQQSASAS VPKNPLLHLK AAVKEKKRNK KKKTIGSPKR IQSPLNNKLL NSPAKTLPGA CGSPQKLIDG FLKHEGPPAE KPLEELSAST SGVPGLSSLQ SDPAGCVRPP APNLAGAVEF NDVKTLLREW ITTISGWLGL C
靶标信息
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIBP80; Alpha integrin-binding protein 80; DNA repair protein REV1; REV1 homolog; REV1, polymerase (DNA directed); REV1- like; Rev1-like terminal deoxycytidyl transferase
基因别名: 1110027I23Rik; AIBP80; AU022044; REV1; REV1L
UniProt ID: (Human) Q9UBZ9, (Mouse) Q920Q2
Entrez Gene ID: (Human) 51455, (Mouse) 56210, (Rat) 316344
damaged DNA binding
protein binding
deoxycytidyl transferase activity
metal ion binding
magnesium ion binding
DNA binding
telomerase activity
RNA helicase activity
DNA-directed DNA polymerase activity
DNA primase activity
sulfate adenylyltransferase activity
RNA guanylyltransferase activity
tRNA guanylyltransferase activity
mannose-phosphate guanylyltransferase activity
transferase activity
nucleotidyltransferase activity
DNA/RNA helicase activity
CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity
phospholactate guanylyltransferase activity
ATP:coenzyme F420 adenylyltransferase activity
UDP-N-acetylgalactosamine diphosphorylase activity
DNA metabolism protein
nucleic acid metabolism protein
