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Invitrogen
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Immunogen sequence: TNLNPSTCPS RPSVQSSHFP SGSYSVRDVF QVQKAKKSTE EEHKEVFRAA VDLEISSASR TCTFLPPFPA HLPTSPDTNK AESSGKWNGL HTPVSVQSRL NLSIEVPSPS QLDQSVLEAL PPDLREQVEQ VCAVQ
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 70%.
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。