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Invitrogen
RG1 Biosimilar Recombinant Human Monoclonal Antibody
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产品信息
MA5-58949
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term 19G9.
靶标信息
RG1 is a gene that has primarily been studied in the context of Ginsenoside Rg1, a bioactive compound derived from the roots of Panax ginseng. Ginsenoside Rg1 is known for its neuroprotective effects and regulatory role in immune responses. It modulates various signaling pathways, including the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, which is crucial for cell survival and growth. Additionally, Rg1 has been shown to inhibit apoptotic pathways mediated by endoplasmic reticulum stress and the c-Jun N-terminal kinase (JNK) pathway in neurodegenerative disease models, potentially offering therapeutic benefits in conditions like Alzheimer's disease. Furthermore, Rg1 influences the activation of astrocytes through long non-coding RNAs (lncRNAs) and microRNAs, contributing to the repair of spinal cord injuries. Overall, RG1, through its association with Ginsenoside Rg1, plays a significant role in cellular protection and modulation across various biological systems.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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