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Invitrogen
RGN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100316
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RGN(Accession Q15493), corresponding to amino acid residues C78-E128.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total RGN/SMP30.
靶标信息
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gluconolactonase; GNL; RC; Regucalcin; Senescence marker protein 30; SMP-30
基因别名: AI265316; GNL; Rc; Reguc; RGN; SMP30
UniProt ID: (Rat) Q03336, (Mouse) Q64374
Entrez Gene ID: (Rat) 25106, (Mouse) 19733
kidney development
liver development
negative regulation of protein phosphorylation
negative regulation of protein kinase activity
cellular calcium ion homeostasis
spermatogenesis
aging
positive regulation of triglyceride biosynthetic process
positive regulation of glucose metabolic process
positive regulation of phosphatase activity
L-ascorbic acid biosynthetic process
negative regulation of phosphoprotein phosphatase activity
positive regulation of ATPase activity
negative regulation of GTPase activity
negative regulation of apoptotic process
positive regulation of GTPase activity
negative regulation of nitric oxide biosynthetic process
positive regulation of fatty acid biosynthetic process
negative regulation of epithelial cell proliferation
regulation of calcium-mediated signaling
negative regulation of cyclic-nucleotide phosphodiesterase activity
liver regeneration
negative regulation of sperm motility
positive regulation of superoxide dismutase activity
positive regulation of calcium-transporting ATPase activity
negative regulation of RNA biosynthetic process
negative regulation of bone development
positive regulation of proteolysis involved in cellular protein catabolic process
negative regulation of calcium-dependent ATPase activity
negative regulation of DNA catabolic process
positive regulation of dUTP diphosphatase activity
negative regulation of leucine-tRNA ligase activity
negative regulation of DNA biosynthetic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
