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Invitrogen
RGS13 Polyclonal Antibody
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产品信息
PA1-28140
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptidecorresponding to amino acids 42-99 of RGS13.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-28140 detects RGS13 from rat, mouse, human samples.
PA1-28140 has been successfully used in Western blot applications.
The PA1-28140 immunogen is: Synthetic peptidecorresponding to amino acids 42-99 of RGS13.
靶标信息
RGS13 is the smallest member of the mammalian gene family, RGS (regulators of G protein-signaling) which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits. RGS13 has been found most abundantly in human tonsil, thymus, lung, lymph node, and spleen. RGS13 regulate Gai, Gaq, and Gas coupled signaling cascades. It is a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors. The protein also attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation. The gene encoding for human RGS13 is localized on chromosome 1q31.2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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