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Proteintech
RNF220 Polyclonal Antibody
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产品信息
32482-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RNF220 fusion protein Ag36190
偶联物
形式
Liquid
浓度
400 µg/mL
规格
60 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: SKNSLLKDAM APGTPKSLLL SASIKREGES PTASPHSSAT DDLHHSDRYQ TFLRVRANRQ TRLNARIGKM KRRKQDEGQR EGSCMAEDDA VDIEHENNNR FEEYEWCGQK RIRATTLLEG GFRGSGFIMC SGKENPDSDA DLDVDGDDTL EYGKPQYTEA DVIPCTGEEP GEAKEREALR GAVLNGGPPS TRITPEFSKW ASDEMPSTSN GESSKQEAMQ KTCKNSDIEK ITEDSAVTTF EALKARVREL ERQLSRGDRY KCLICMDSYS MPLTSIQCWH VHCEECWLRT LGAKKLCPQC NTITAPGDLR RIYL
靶标信息
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase RNF220; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220; unnamed protein product
基因别名: 4732477A13; 4931406I20Rik; 5730503K05Rik; AV302541; C1orf164; HLD23; RNF220
UniProt ID: (Human) Q5VTB9, (Mouse) Q6PDX6
Entrez Gene ID: (Human) 55182, (Rat) 500532, (Mouse) 66743
ubiquitin-protein transferase activity
protein binding
beta-catenin binding
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protein ubiquitination
protein autoubiquitination
positive regulation of canonical Wnt signaling pathway
noradrenergic neuron development
protein monoubiquitination
dorsal/ventral neural tube patterning
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of postsynaptic neurotransmitter receptor internalization
regulation of transcription regulatory region DNA binding
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