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Bioss
RNF74 Polyclonal Antibody
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产品信息
BS-6941R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human RAG1/RNF74, amino acids 351-450.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC43321; RAG-1; RAG-1 Antibody; recombinase activating gene 1; recombination activating gene 1 Antibody; recombination activating protein 1; recombination activation protein 1; recombination-activating gene 1; RING finger protein 74; RNF74 Antibody; V(D)J recombination-activating protein 1
基因别名: RAG-1; RAG1; RNF74
UniProt ID: (Human) P15918, (Mouse) P15919
Entrez Gene ID: (Human) 5896, (Rat) 84600, (Mouse) 19373
DNA binding
endonuclease activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
histone binding
protein homodimerization activity
sequence-specific DNA binding
metal ion binding
ubiquitin protein ligase activity
molecular_function
nucleic acid binding
catalytic activity
nuclease activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
hydrolase activity
hydrolase activity, acting on ester bonds
acid-amino acid ligase activity
ribosomal S6-glutamic acid ligase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
retroviral 3' processing activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
DNA metabolism protein
endodeoxyribonuclease
nucleic acid metabolism protein
adaptive immune response
pre-B cell allelic exclusion
DNA recombination
immune response
histone monoubiquitination
B cell differentiation
T cell differentiation in thymus
V(D)J recombination
T cell homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of T cell differentiation
thymus development
protein autoubiquitination
negative regulation of thymocyte apoptotic process
nucleic acid phosphodiester bond hydrolysis
metabolic process
obsolete death
chromatin modification
regulation of T cell differentiation
negative regulation of T cell apoptotic process
