Abnova

ROCK2 Recombinant Rabbit Monoclonal Antibody

查看其他30个ROCK2抗体

问题与答案

问题与答案

问题与答案

Additional Information:

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抗体检测数据 (2)

ROCK2 Antibody in Immunocytochemistry (ICC/IF)

ROCK2 Antibody in Immunocytochemistry (ICC/IF)

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ROCK2 Antibody (RAB01725) in ICC/IF

Immunocytochemical staining of Hela with ROCK2 recombinant monoclonal antibody, clone R01-4F1 (Product # RAB01725). (A) ROCK2 (green) and (B) DAPI (blue).

ROCK2 Antibody in Immunocytochemistry (ICC/IF)

ROCK2 Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

ROCK2 Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemical staining of Hela with ROCK2 recombinant monoclonal antibody, clone R01-4F1 (Product # RAB01725). (A) ROCK2 (green) and (B) DAPI (blue).

ROCK2 Antibody in Western Blot (WB) — Western blot analysis of ROCK2 in Hela, rat Brain, K562 lysates using human ROCK2 recombinant monoclonal antibody, clone R01-4F1 (Product # RAB01725).

产品信息

RAB01725

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

免疫细胞化学 (ICC/IF)

1:50-1:200

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

CHO cells

分类

Recombinant Monoclonal

类型

Antibody

抗原

Synthetic peptide corresponding to human ROCK2.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA

内含物

0.01% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

ROCK2, the predominant ROCK isoform in skeletal muscle, is an important regulator downstream of Rho GTPases. ROCK2 regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: p164 ROCK-2; rho-associated, coiled-coil-containing protein kinase II; ROCK II; rockii; unnamed protein product

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基因别名: ROCK-II

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UniProt ID: (Human) O75116

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Entrez Gene ID: (Human) 9475

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protease binding RNA binding protein kinase activity protein serine/threonine kinase activity structural molecule activity protein binding ATP binding small GTPase binding tau protein binding tau-protein kinase activity endopeptidase activator activity Rho-dependent protein serine/threonine kinase activity protein serine kinase activity

mitotic cytokinesis epithelial to mesenchymal transition response to ischemia aortic valve morphogenesis protein phosphorylation smooth muscle contraction signal transduction Rho protein signal transduction positive regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression positive regulation of centrosome duplication negative regulation of angiogenesis actin cytoskeleton organization regulation of cell adhesion positive regulation of cell migration cortical actin cytoskeleton organization actomyosin structure organization regulation of neurological system process positive regulation of connective tissue growth factor production regulation of actin cytoskeleton organization regulation of circadian rhythm positive regulation of MAPK cascade modulation by host of viral process negative regulation of nitric oxide biosynthetic process regulation of keratinocyte differentiation embryonic morphogenesis centrosome duplication regulation of stress fiber assembly positive regulation of stress fiber assembly regulation of focal adhesion assembly mRNA destabilization negative regulation of biomineral tissue development response to transforming growth factor beta protein localization to plasma membrane positive regulation of fibroblast growth factor production regulation of blood vessel diameter regulation of angiotensin-activated signaling pathway negative regulation of protein localization to lysosome regulation of cellular response to hypoxia regulation of cell junction assembly regulation of beta-amyloid formation positive regulation of beta-amyloid formation positive regulation of protein localization to early endosome positive regulation of amyloid precursor protein catabolic process regulation of establishment of endothelial barrier negative regulation of bicellular tight junction assembly cellular response to acetylcholine positive regulation of connective tissue replacement response to angiotensin regulation of establishment of cell polarity regulation of cell motility