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Invitrogen
RPA14 Polyclonal Antibody
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产品信息
PA5-89599
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 6-121 of human RPA3 (NP_0029381)
偶联物
形式
Liquid
浓度
2.14 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DLPRSRINAG MLAQFIDKPV CFVGRLEKIH PTGKMFILSD GEGKNGTIEL MEPLDEEISG IVEVVGRVTA KATILCTSYV QFKEDSHPFD LGLYNEAVKI IHDFPQFYPL GIVQHD; Positive Samples: Mouse spleen; Cellular Location: Nucleus
靶标信息
Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Replication factor A protein 3; Replication protein A 14 kDa subunit; replication protein A3, 14kDa; RF-A protein 3; RP-A p14
基因别名: 14kDa; C330026P08Rik; REPA3; RP-A p14; RPA14; RPA3
UniProt ID: (Human) P35244, (Mouse) Q9CQ71
Entrez Gene ID: (Human) 6119, (Mouse) 68240, (Rat) 296883
double-strand break repair via homologous recombination
DNA replication
DNA repair
base-excision repair
nucleotide-excision repair
mismatch repair
DNA recombination
cellular response to DNA damage stimulus
regulation of mitotic cell cycle
regulation of cell proliferation
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
