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Invitrogen
RPA70 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-21976
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human RPA70. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse liver.
Predicted reactivity: Mouse (87%), Rat (85%), Sheep (93%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MSTP075; replication factor A protein 1; replication protein A1, 70kDa; RF-A protein 1; RP-A p70; single-stranded DNA-binding protein; unnamed protein product
Gene Aliases: 5031405K23Rik; 70kDa; HSSB; MST075; PFBMFT6; REPA1; RF-A; RP-A; Rpa; RPA70
UniProt ID: (Human) P27694, (Mouse) Q8VEE4
Entrez Gene ID: (Human) 6117, (Mouse) 68275
telomere maintenance
double-strand break repair via homologous recombination
in utero embryonic development
DNA replication
DNA repair
base-excision repair
nucleotide-excision repair
mismatch repair
DNA recombination
chromatin organization
cellular response to DNA damage stimulus
telomere maintenance via telomerase
positive regulation of cell proliferation
hemopoiesis
protein localization to chromosome
homeostasis of number of cells within a tissue
chromosome organization
meiotic cell cycle
protein localization to site of double-strand break
DNA-dependent DNA replication
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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