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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: NVIISSAAER PLEIRGPYDV ANLGLLFGLS ESDAKAAVST NCRAALLHGE TRKTAFGIIS TVKKPRPSEG DEDCLPASKK AKCEG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.
RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ribonuclease P/MRP 30kDa subunit; RNase P subunit 2; RNaseP protein p30; unnamed protein product
基因别名: TSG15
UniProt ID: (Human) P78346
Entrez Gene ID: (Human) 10556