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Invitrogen
RSK4 Polyclonal Antibody
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RSK4 Antibody (PA5-90097) in WB
Western blot analysis of RSK4 in mouse kidney. Samples were incubated with RSK4 Polyclonal antibody (Product # PA5-90097) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
产品信息
PA5-90097
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_0553111)
偶联物
形式
Liquid
浓度
1.47 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GGNWDNISDG AKDLLSHMLH MDPHQRYTAE QILKHSWITH RDQLPNDQPK RNDVSHVVKG AMVATYSALT HKTFQPVLEP VAASSLAQRR SMKKRTSTGL; Positive Samples: Mouse kidney; Cellular Location: Cytoplasm, Nucleus, cytosol
靶标信息
RPS6KA6 (RSK4) is a member of the RSK kinases family. RSK family members are activated by ERKs and mitogens and are unusual in that they contain 2 non-identical kinase domains. RSK4 encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ribosomal protein S6 kinase alpha-6; S6K-alpha-6; S6KA6
基因别名: 2610524K04Rik; Rps6ka6; RSK4; S6K-alpha-6
UniProt ID: (Mouse) Q7TPS0
Entrez Gene ID: (Mouse) 67071
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
ribosomal protein S6 kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
regulation of translation
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
phosphorylation
intracellular signal transduction
negative regulation of embryonic development
negative regulation of ERK1 and ERK2 cascade
negative regulation of mesoderm development
