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Invitrogen
RSV M2 Polyclonal Antibody
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产品信息
PA1-4183
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues L(81) E S Y I G S I N NI T K Q S A(95) of the human RSV M2 protein, which is a CTL epitope.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-4183 detects Respiratory Syncytial Virus M2 Protein from infected samples.
PA1-4183 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~20 kDa protein representing RSV M2 in infected HEp-2 cells.
The PA1-4183 immunogen is a synthetic peptide corresponding to residues L(81) E S Y I G S I N NI T K Q S A(95) of the human RSV M2 protein, which is a CTL epitope. This sequence is 93% conserved in bovine.
靶标信息
The RSV (Respiratory Syncytial Virus) M2 gene encodes for two critical proteins, M2-1 and M2-2. The M2-1 protein is essential for viral transcription, acting as an elongation factor, ensuring the synthesis of full-length viral mRNAs. It associates non-covalently with the viral RNA-dependent RNA polymerase complex. Transcription regulation is influenced by the phosphorylation state of M2-1, mediated by cellular protein phosphatase 1 (PP1). In contrast, the M2-2 protein plays a significant role in regulating the balance between viral transcription and replication. These functions underscore the crucial roles of M2 gene products in the RSV lifecycle and their importance as potential targets for antiviral strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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