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Proteintech
RTKN Polyclonal Antibody
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产品信息
12762-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RTKN Fusion Protein Ag3265 (201-550 aa encoded by BC017727)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ATKLSSSLG RSSGRRVRAS LDSAGGSGSS PILLPTPVVG GPRYHLLAHT TLTLAAVQDG FRTHDLTLAS HEENPAWLPL YGSVCCRLAA QPLCMTQPTA SGTLRVQQAG EMQNWAQVHG VLKGTNLFCY RQPEDADTGE EPLLTIAVNK ETRVRAGELD QALGRPFTLS ISNQYGDDEV THTLQTESRE ALQSWMEALW QLFFDMSQWK QCCDEIMKIE TPAPRKPPQA LAKQGSLYHE MAIEPLDDIA AVTDILTQRE GARLETPPPW LAMFTDQPAL PNPCSPASVA PAPDWTHPLP WGRPRTFSLD AVPPDHSPRA RSVAPLPPQR SPRTRGLCSK GQPRTWLQSP V (201-550 aa encoded by BC017727)
靶标信息
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rhotekin; RTKN; rtkn {ECO:0000312|RGD:727874}
基因别名: RTKN; RTKN1
UniProt ID: (Human) Q9BST9, (Rat) Q6V7V2, (Mouse) Q8C6B2
Entrez Gene ID: (Human) 6242, (Rat) 297383, (Mouse) 20166
