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Proteintech
RXRB Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
14684-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RXRB Fusion Protein Ag0263 (70-238 aa encoded by BC001167)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.21 mg/mL
规格
31.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can recognize the RXR beta protein and detects a 58 kDa band.
Immunogen sequence: RDGMGDSGR DSRSPDSSSP NPLPQGVPPP SPPGPPLPPS TAPSLGGSGA PPPPPMPPPP LGSPFPVISS SMGSPGLPPP APPGFSGPVS SPQINSTVSL PGGGSGPPED VKPPVLGVRG LHCPPPPGGP GAGKRLCAIC GDRSSGKHYG VYSCEGCKGF FKRTIRKDLT (70-238 aa encoded by BC001167)
靶标信息
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DADB-100D22.1; MGC1831; MHC class I promoter binding protein; MHC class I regulatory element-binding protein H-2RIIBP; nuclear receptor co-regulator 1; nuclear receptor coregulator 1; Nuclear receptor subfamily 2 group B member 2; putative new variant; putative retinoid X receptor beta; Retinoic acid receptor RXR-beta; retinoic acid receptor, beta; retinoid X receptor; Retinoid X receptor beta; RXR Beta; unnamed protein product
基因别名: AL023085; DAUDI6; H-2RIIBP; NR2B2; RCoR-1; Rub; RXR-beta; RXRB; RXRbeta
UniProt ID: (Mouse) P28704
Entrez Gene ID: (Human) 6257, (Rat) 361801, (Mouse) 20182
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
chromatin DNA binding
sequence-specific DNA binding
retinoic acid-responsive element binding
sequence-specific double-stranded DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
9-cis retinoic acid receptor activity
thyroid hormone receptor coactivator activity
protein homodimerization activity
vitamin D receptor binding
retinoic acid receptor binding
transcription regulatory region DNA binding
thyroid hormone receptor binding
protein heterodimerization activity
metal ion binding
C4 zinc finger nuclear receptor
regulation of transcription, DNA-templated
nervous system development
hormone-mediated signaling pathway
cell differentiation
positive regulation of bone mineralization
intracellular steroid hormone receptor signaling pathway
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
cellular response to retinoic acid
in utero embryonic development
maternal placenta development
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of myelination
steroid hormone mediated signaling pathway
ventricular cardiac muscle cell differentiation
cardiac muscle cell proliferation
positive regulation of receptor activity
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