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Invitrogen
RXRB Monoclonal Antibody (147)
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产品信息
MA1-4669
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
147
抗原
Synthetic peptide corresponding to the hinge region of mouse RXRB conjugated to KLH
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is specific for the ~48 kDa RXR-beta protein.
靶标信息
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DADB-100D22.1; MGC1831; MHC class I regulatory element-binding protein H-2RIIBP; nuclear receptor co-regulator 1; nuclear receptor coregulator 1; Nuclear receptor subfamily 2 group B member 2; putative retinoid X receptor beta; Retinoic acid receptor RXR-beta; retinoic acid receptor, beta; retinoid X receptor; Retinoid X receptor beta; RXR Beta
基因别名: AL023085; H-2RIIBP; Nr2b2; RCoR-1; Rub; RXR-beta; Rxrb
UniProt ID: (Mouse) P28704
Entrez Gene ID: (Rat) 361801, (Mouse) 20182
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
9-cis retinoic acid receptor activity
zinc ion binding
thyroid hormone receptor coactivator activity
protein homodimerization activity
vitamin D receptor binding
retinoic acid receptor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
thyroid hormone receptor binding
protein heterodimerization activity
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
metal ion binding
C4 zinc finger nuclear receptor
in utero embryonic development
maternal placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of myelination
steroid hormone mediated signaling pathway
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
ventricular cardiac muscle cell differentiation
cardiac muscle cell proliferation
cellular response to retinoic acid
positive regulation of receptor activity
