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Huabio
Rabbit IgG Kappa Light Chain Monoclonal Antibody (1-14)
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产品信息
M0809-1
应用
建议稀释比
已发表文章
产品规格
种属反应
Rabbit
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1-14
抗原
Purified Rabbit IgG kappa Light Chain.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.2% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The fundamental structure of IgG contains two identical heavy chains of about 50 kDa and two identical light chains of about 25 kDa, thus tetrameric quaternary structure. Light chain, which is usually same in a natural IgG molecule, includes kappa chain and lambda chain, but kappa or lambda antibody can exist in one body simultaneously. A heavy chain includes Fab- and Fc-Fragments. The most common type of myeloma is IgG kappa. In IgG kappa myeloma, the myeloma cells produce an immunoglobulin made from two IgG heavy chains bound to two kappa light chains. About 15% of patients have light chain myeloma. In this type of myeloma, the myeloma cells secrete only light chain protein and no heavy chains.
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