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Active Motif
RbAp46/48 Polyclonal Antibody
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产品信息
39198
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This RbAp46/48 antibody was raised against recombinant human RbAp46 protein.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum with 30% glycerol
内含物
0.035% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
RbAp48-15G12 recognizes full length RbAp48 (48 kDa) and RbAp46 (46 kDa), related nuclear proteins first isolated by their ability to interact with the carboxyl-terminus of the retinoblastoma protein (Rb). These two proteins are highly homologous at the amino acid level and are related functionally to members of the WD (Trp-Asp) repeat family of proteins. RbAp48 is one of the three subunits of CAF-1, can bind to histone H4 and is a subunit of human histone deacetylase HD1. Both RbAp48 and RbAp46 interact with HDAC1 and mSin3 in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; Chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; G1/S transition control protein-binding protein RbAp46; Histone acetyltransferase type B subunit 2; Histone-binding protein RBBP4; Histone-binding protein RBBP7; MSI1 protein homolog; Nucleosome-remodeling factor subunit RBAP46; Nucleosome-remodeling factor subunit RBAP48; RBBP-4; RBBP-7; retinoblastoma binding protein 4; retinoblastoma binding protein 7; Retinoblastoma-binding protein 4; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46; Retinoblastoma-binding protein p48; retinoblastoma-binding protein RbAp46
基因别名: lin-53; NURF55; RBAP46; RBAP48; RBBP4; RBBP7
UniProt ID: (Human) Q09028, (Human) Q16576
Entrez Gene ID: (Human) 5928, (Human) 5931
negative regulation of transcription from RNA polymerase II promoter
DNA replication
transcription, DNA-templated
multicellular organism development
cell proliferation
histone deacetylation
negative regulation of cell growth
CENP-A containing nucleosome assembly
negative regulation of gene expression, epigenetic
response to steroid hormone
cellular heat acclimation
regulation of signal transduction by p53 class mediator
DNA replication-dependent nucleosome assembly
DNA replication-independent nucleosome assembly
chromatin remodeling
regulation of transcription, DNA-templated
cell cycle
negative regulation of cell proliferation
chromatin assembly
ATP-dependent chromatin remodeling
regulation of cell cycle
