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Invitrogen
Roxarsone Recombinant Mouse Monoclonal Antibody (3G3)
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Roxarsone Antibody (MA566330) in SDS-PAGE
SDS-PAGE characterization of Roxarsone under reducing conditions. Lane M: Protein marker (kDa); Lane ROX: Purified Roxarsone Recombinant Monoclonal (Product # MA566330). Roxarsone showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-438.
产品信息
MA566330
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3G3
抗原
Conjugate of ROX hapten and KLH.
偶联物
形式
Liquid
浓度
3.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Roxarsone, also known as 4-hydroxy-3-nitrobenzenearsonate, is an organoarsenic compound extensively utilized as a coccidiostat in poultry feed to promote growth by enhancing feed efficiency and increasing bird weight. Structurally, it is characterized by its benzene ring linked to arsenic, indicative of its potent antimicrobial properties. Roxarsone is metabolized in the environment into various arsenic species, contributing to ecological concerns such as arsenic contamination in aquatic and soil systems. Its interaction with biological systems can lead to toxic effects, as seen in its capacity to enhance endothelial cell growth and facilitate angiogenesis via the VEGF/Flk1 mechanism. Moreover, microbial activity plays a substantial role in the bioreduction of roxarsone, with ongoing research focused on its degradation pathways and the development of functional materials for its selective adsorption and removal. These studies are vital for mitigating the environmental and health implications associated with roxarsone usage in agriculture.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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