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Invitrogen
SAP30L Polyclonal Antibody
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产品信息
PA1-4371
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: V(165) K S N K S R L D Q K S E G G K Q L E(183)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-4371 detects SAP30L from human samples.
PA1-4371 has been successfully used in Western blot procedures.
PA1-4371 immunizing peptide corresponds to amino residues 165-183 from human SAP30L Protein.
靶标信息
A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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