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Fabgennix
SAPOSIN-D Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
SAPC-101AP
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 438-519 on mouse Saposin-D.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Saposin D is a small, non-enzymatic lysosomal protein that promotes the degradation of ceramide and other sphingolipids by making them accessible to lysosomal enzymes. It is one of the four saposins derived from prosaposin and plays an important role in lysosomal lipid homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); snoRNA MBII-198; sphingolipid activator protein; sulfated glycoprotein 1; sulfated glycoprotein precursor; unnamed protein product
基因别名: SGP-1; SGP1A
Entrez Gene ID: (Mouse) 19156, (Rat) 25524
G-protein coupled receptor binding
protease binding
protein binding
phospholipid binding
lipid binding
sphingolipid activator protein activity
lipid antigen binding
identical protein binding
protein homodimerization activity
scaffold protein binding
ganglioside GM1 binding
ganglioside GM2 binding
ganglioside GM3 binding
ganglioside GT1b binding
ganglioside GP1c binding
lipid chaperone activity
NK T cell differentiation
corneocyte development
lipid metabolic process
glycolipid metabolic process
sphingolipid metabolic process
ceramide metabolic process
glucosylceramide metabolic process
galactosylceramide catabolic process
sphingomyelin catabolic process
intracellular protein transport
lysosomal transport
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
sensory perception of sound
protein secretion
gene expression
regulation of lipid metabolic process
antigen processing and presentation
cerebellar Purkinje cell differentiation
sphingolipid catabolic process
cellular response to reactive oxygen species
myelination
regulation of MAPK cascade
positive regulation of MAPK cascade
developmental growth
neurological system process
neuromuscular process controlling balance
positive regulation of hydrolase activity
micturition
prostate gland growth
epithelial cell differentiation involved in prostate gland development
inclusion body assembly
cochlea development
walking behavior
cornified envelope assembly
lysosomal protein catabolic process
ganglioside GM1 transport to membrane
glycolipid transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
