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Invitrogen
SARS-CoV/SARS-CoV-2 NP Monoclonal Antibody (3863)
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产品信息
MA5-47523
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
3863
抗原
Proprietary sequence
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.1% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specificity: Specific for the nucleoprotein of the SARS virus (IFA & ELISA) and COVID-19 virus (ELISA). Negative for human coronaviruses 229E & OC43. Reactive with the nucleocapsids of Variants: UK B.1.1.7, SA B.1.351, Brazil P.1 & B.1.617.2.
Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 µg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 mL. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.
靶标信息
Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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